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Levodropropizine for treating cough in adult and children: a meta-analysis of…
Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and lung specialists. About 40% of the population at any one time report cough. Cough is associated with significantly impaired health-related quality of life. evodropropizine is an effective and very well tolerated peripheral antitussive drug. We want to compare it to central cough…
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Levodropropizine-Induced Anaphylaxis: Case Series and Literature Review
Levodropropizine is commonly used as an antitussive drug for acute and chronic cough. It is a non-opioid agent with peripheral antitussive action via the modulation of sensory neuropeptide levels in the airways. Thus, levodropropizine has a more tolerable profile than opioid antitussives. However, we experienced 3 cases of levodropropizine-induced anaphylaxis. Three patients commonly presented …
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Current and new challenges in occupational lung diseases
Occupational lung diseases are an important public health issue and are avoidable through preventive interventions in the workplace. Up-to-date knowledge about changes in exposure to occupational hazards as a result of technological and industrial developments is essential to the design and implementation of efficient and effective workplace preventive measures.
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Asthma: definitions and pathophysiology
Asthma is a common condition due to chronic inflammation of the lower respiratory tract. Chronic lower airway inflammation is known to be more common in individuals that also have inflammatory disorders of the upper airway. The scientific understanding of asthma continues to improve and it is important for providers who treat upper or lower airway inflammation to be familiar with asthma’s def…
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Asthma and Exercise-Induced Bronchoconstriction in Athletes
Regular exercise is one of the most effective means to maintain good health. A substantial proportion of the general population engages in competitive sports, including many people with asthma; when controlled, asthma does not restrict exercise performance. Indeed, exercise training can improve asthma symptoms, quality of life, exercise capacity, and pulmonary function, as well as reduce airwa…
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Patient Information Series : What Is Asthma?
Asthma is a chronic disease that affects the airways of your lungs. Your airways are the breathing tubes that carry air in and out of your lungs. When you have asthma, your airways become swollen
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SERPINA1 and MAN1B1 polymorphisms are not linked to severe liver disease in a…
Fifteen to twenty percent of alpha-1 antitrypsin deficiency patients (A1ATD) have a severe liver outcome (portal hypertension -PHT) during childhood. Since they all share the same ZZ SERPINA1 genotype and that environmental factors such as alcohol cannot be advanced, the presence of modifier genes is now well recognized. SNPs located on the SERPINA1 and MAN1B1 genes have already been tes…
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An Experimental Study of the Effect of Chronic Atelectasis on Pulmonary and B…
Four dogs and one patient with uncomplicated atelectasis of an entire lung were studied. Arterial oxygen saturations were nearly normal, indicating diminished flow to the atelectatic lung. Angiography confirmed this finding. "Vinyl plastic injections showed no evidence of increased bronchial collateral circulation and pathological examination of the atelectatic lung did not demonstrate any …
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Diagnosis and management of chronic cough: similarities and differences betwe…
Cough is a natural process that protects the airway. Cough can occur spontaneously or voluntarily. It is considered chronic when it is present for longer than 4 weeks in children or 8 weeks in adults. In both, chronic cough causes patient distress and increased healthcare utilization. Etiologies of pediatric chronic cough include asthma, protracted bacterial bronchitis, tracheomalacia, habit co…
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Risk Factors for Chronic Cough in Young Children: A Cohort Study
Data on the predictors of chronic cough development in young children are scarce. Our primary objective was to examine the factors associated with young children developing a chronic cough, with a focus on childcare attendance
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