Advances in radionuclide imaging of cardiac sarcoidosis

Radionuclide imaging for the diagnosis and monitoring of cardiac involvement in sarcoidosis has advanced significantly in recent years.

EARLY FLUID RESUSCITATION OF END STAGE RENAL DISEASE PATIENTS WITH SEVERE SEP…

The Surviving Sepsis (SS) Guidelines recommend early, aggressive fluid resuscitation with 30mL/kg crystalloid for hypotension or lactate >4mmol/L within the first 3hours of suspected sepsis (t S-3). These guidelines are not always applied to septic patients with end stage renal disease (ESRD) due to fear of developing complications. We hypothesized that ESRD patients with severe sepsis (with h…

Risk Factors and Stroke Characteristic in Patients with Postoperative Strokes

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Physical inactivity is a strong risk factor for stroke in the oldest old: Fin…

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Thrombosis in pregnancy : update in diagnosis and management

Acute venous thromboembolism poses significant problems in pregnancy, a time when objective diagnosis and prompt treatment are essential. Events can occur at any stage in pregnancy, but the period of greatest risk is in the weeks after delivery. Ultrasound venography remains the diagnostic technique of choice for deep venous thrombosis. For pulmonary thromboembolism, ventilation perfusion lung…

Deep vein thrombosis: pathogenesis, diagnosis, and medical management

Deep vein thrombosis (DVT) is a major preventable cause of morbidity and mortality worldwide. Venous thromboembolism (VTE), which includes DVT and pulmonary embolism (PE), affects an estimated 1 per 1,000 people and contributes to 60,000–100,000 deaths annually. Normal blood physiology hinges on a delicate balance between pro- and anti-coagulant factors. Virchow’s Triad distills the multi…

Deep venous thrombosis: a literature review

Abstract: Deep vein thrombosis (DVT) refers to the formation of thrombosis within the deep veins, dominantly occurring in the pelvis or lower limbs. This clinical syndrome has gained attention as one complication of DVT, pulmonary embolization, can be fatal. Therefore, early detection and systematic management of DVT and related complica tions are essential in clinical practice. As the clinica…

Renin Angiotensin System and Cytokines in Chronic Kidney Disease: Clinical an…

Chronic kidney disease (CKD) has been considered an important publichealth issue in all countries. Experimental and clinical studies support the general idea that the pathophysiology of CKD is associated with the interaction of several endogenous mediators, in-cluding components of therenin-angiotensin system(RAS) and cytokines

β-Thalassemia

β-Thalassemia is caused by reduced (β+) or absent (β0) synthesis of the β-globin chains of hemoglobin. Three clinical and hematological conditions of increasing severity are recognized: the β-thalassemia carrier state, thalassemia intermedia, and thalassemia major, a severe transfusion-dependent anemia. The severity of disease expression is related mainly to the degree of α-globin chain e…

The Role of MicroRNAs in Myocardial Infarction: From Molecular Mechanism to C…

MicroRNAs (miRNAs) are a class of small single-stranded and highly conserved non-coding RNAs, which are closely linked to cardiac disorders such as myocardial infarction (MI), cardiomyocyte hypertrophy, and heart failure. A growing number of studies have demonstrated that miRNAs determine the fate of the heart by regulating cardiac cell death and regeneration after MI. A deep understanding of …