There are currently more than 117 million people with diabetes worldwide. WHO figures estimate that this will rise to 300 million in 2025. Diabetes is the fourth main course of death in most developed countries. It is estimated that diabetes accounts for 5–10% of the nation’s health budget. The estimated diabetes prevalence varies between different countries (5 to 20%), but an increase in a…
In slowing kidney progression, numerous pre-dialysis chronic kidney disease (CKD) patients could not adhere to the well-established dietary pattern, including a very low protein diet, 0.3–0.4 g/kg/ day, plus a full dose ketoanalogues (KAs) of amino acids. We evaluated the role of a low protein diet (LPD), 0.6–0.8 g/kg/day, combined with KAs (LPD–KAs) on CKD progression. We extracted data …
Dietary protein restriction may improve determinants of CKD progression. However, the extent of improvement and effect of ketoanalogue supplementation are unclear. We conducted a prospective, randomized, controlled trial of safety and efficacy of ketoanalogue–supplemented vegetarian very low–protein diet (KD) compared with conventional low–protein diet (LPD). Primary end point was RRT ini…
Blood pressure (BP) is hardly controlled in chronic kidney disease (CKD). We compared the effect of very low protein diet (VLPD) supplemented with ketoanalogs of essential amino acids (0.35 g/kg/day), low protein diet (LPD, 0.60 g/kg/ day), and free diet (FD) on BP in patients with CKD stages 4 and 5.
A low-protein diet (LPD) is a conservative treatment in patients with chronic kidney disease (CKD) to improve uremic symptoms and slow the progression of renal dysfunction. However, the deleterious effects of protein restriction on nutritional status have raised concern. We investigated whether ketoanalogs supplementation in CKD patients who had training on LPD retards the progression of CKD an…
PROTEIN-RESTRICTED DIETS SUPPLE-MENTED with keto/amino acids should be considered as one of the main approaches in the management program of chronic kidney disease (CKD) patients
Pengumpulan sampel pada penelitian ini dilakukan selama 6 bulan yaitu mulai bulan Oktober 2004 – Maret 2005. Selama periode tersebut didapatkan 44 penderita yang dapat dievaluasi serta dilakukan analisis, yaitu masing-masing 22 penderita pada kelompok perlakuan dan 22 penderita pada kelompok kontrol
Berbicara Pharmacovigilance tidak terlepas dari efek samping obat dan pemantauan keamanan obat, Apa hubungannya efek samping obat dengan Pharmacovigilance? Apakah efek samping bisa diprediksi atau justru bisa dihindari? Apakah obat dijamin aman dengan adanya Pharmacovigilance ? Ayo ikuti Sharing Knowledge Session yang akan mengupas PV secara lebih chill dan fun agar mudah dipahami untuk pemant…
Effective antihypertensive therapy is essential for achieving optimal blood pressure (BP) control and reducing cardiovascular events. This double-blind, multicenter, randomized trial aimed to compare the antihypertensive efficacy and safety of a combination of amlodipine (AML) and candesartan cilexetil (CC) versus AML monotherapy in patients with essential hypertension (HTN). After a 4-week run…