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Impact of NSAID etoricoxib on side effects of orthodontic tooth movement
Objectives: The non-steroidal anti-inflammatory drug etoricoxib is the most highly selective inhibitor of cyclooxygenase-2 available (344:1) and has been approved for postoperative pain therapy following dental interventions in Europe. At clinically relevant doses it has been reported to only have marginal effects on the velocity of orthodontic tooth movement (OTM). Its effects on associated …
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The Effects of Non-Steroidal Anti-Inflammatory Drugs Used for Orthodontic Pai…
Orthodontic treatment is commonly associated with pain, leading to reduced patient compliance and treatment adherence. Non-steroidal anti-inflammatory drugs (NSAIDs) are effective in reducing this pain by inhibiting prostaglandin synthesis. However, this mechanism may also interfere with orthodontic tooth movement (OTM) by affecting bone remodeling. This narrative review investigates the exis…
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Analgesic Efficacy of Etoricoxib following Third Molar Surgery: A Meta-analysis
Background. The purpose of this meta-analysis was to assess the clinical efficacy of etoricoxib in comparison with traditional NSAIDs for postoperative pain after third molar surgery. Methods. The quality of studies found in PubMed and Google Scholar was evaluated with Cochrane Collaboration’s risk of bias tool. Data on total consumption of rescue analgesics, number of patients using resc…
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The Efficacy of Oral Etoricoxib in Pain Control During Colposcopy-Directed Ce…
Objective: To investigate the effectiveness and safety of oral etoricoxib administration before colposcopic procedure for pain relief during and after colposcopy. Methods: A prospective double-blind, randomized controlled trial was conducted at the colposcopy unit of Thammasat University Hospital, Thailand from August 2022 to January 2023. The participants were women undergoing colposcopy. …
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Comparing pre‑ and postoperative etoricoxib administration versus only post…
Objectives: This study aimed to compare the impact of pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life. Materials and methods: This prospective quasi experimental study involved 56 patients, divided into a study group receiving preemptive etoricoxib 120 mg before surgery and postoperative etoricoxib…
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Nationwide Etoricoxib Injection Clinical Experience (NICE): Real-World Eviden…
Pain is a major health issue globally. Etoricoxib, a highly selective COX-2 inhibitor, given orally, has been found to be efficacious and safe in the management of acute and chronic pain. Oral etoricoxib has been extensively studied; however, there is a lack of research exploring the use of etoricoxib via alternative routes, specifically intramuscular (IM) injection. This study aimed to evaluat…
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Ankylosing spondylitis, chronic fatigue and depression improved after stromal…
Osteoarthritis is a prevalent chronic disease that impacts quality of life and imposes a heavy economic burden. Despite this there is no confirmed treatment that could prevent progressive destruction of osteoarthritic joints. Mesenchymal stem cells with their regenerative and immunosuppressive properties have emerged as a potential therapy
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Exercise programmes for ankylosing spondylitis (Review)
Exercise programmes are oPen recommended for managing ankylosing spondylitis (AS), to reduce pain and improve or maintain functional capacity
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The genetic basis of ankylosing spondylitis: new insights into disease pathog…
Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and the disease is characterized by inflammation and ankylosis, mainly at the cartilage–bone interface and enthesis. HLA-B27 has been known to be the major AS-susceptibility gene for more than 40 years. Despite advances made in the past few…
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Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease …
Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases
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