Antibiotic stewardship in critical care

Although antibacterial resistance is growing, development of new antibiotics is in decline. Therefore strategies are needed to maintain the effectiveness of current antibiotics for as long as possible. • Infections due to resistant organisms are associated with higher mortality, morbidity, longer hospital stays, and higher health care costs.

How we manage haemostasis during sepsis

Sepsis may be associated with activation of the coagulation system and, in its most severe form, may result in disseminated intravascular coagulation (DIC). Initially, there is thrombosis primarily affecting small and medium sized vessels and contributing to organ dysfunction, but continued activation results in consumption of coagulation factors. This results in prolongation of global coagulat…

Hospital-acquired pneumonia in ICU

The French Society of Anesthesia and Intensive Care Medicine and the French Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) in intensive care unit (ICU). The goal of 16 French-speaking experts was to produce a framework enabling an easier decision-making process for intensivists. The guidelines were related to 3 specific areas related to HAP (prevention…

Early Administration of Antibiotics for Suspected Sepsis

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Tolerability of high-dose ceftriaxone in CNS infections: a prospective multic…

High-dose ceftriaxone for CNS infection administered as recommended by French guidelines in adults was well tolerated overall, suggesting these recommendations could be applied and generalized. In patients with advanced age or renal insufficiency, prescription should be done with caution and therapeutic drug monitoring could be useful.

Infections and risk-adjusted length of stay and hospital mortality in Polish …

The median LOS for neonates with infections was twice as high as for neonates without infection. LOS was significantly affected by the overall general condition of the neonate, as expressed by both gestational age and birth weight as well as by the Clinical Risk Index for Babies (CRIB) score; another independent factor was presence of at least one infection. Risk of in-hospital mortality was…

ANTIBIOTIC HYPERSENSITIVITY REACTIONS AND APPROACHES TO DESENSITIZATION

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Prevalence of the Helicobacter pylori in the tonsils and adenoids

This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas.

Pola Penggunaan Antibiotik Profilaksis pada Pasien Bedah Caesar (Sectio Caesa…

Telah dilakukan penelitian pola penggunaan antibiotik profilaksis pada pasien bedah caesar (Seksio Sesare) di Rumah Sakit Pekanbaru Medical Center (PMC) tahun 2014. Tujuan penelitian ini untuk mengetahui pola penggunaan antibiotik profilaksis bedah sesar. Jenis penelitian yang dilakukan adalah penelitian observasional yang dirancang dengan studi deskriptif dengan cara melakukan kajian terhadap …

EVALUASI PENGGUNAAN ANTIBIOTIK PROFILAKSIS TERHADAP KEJADIAN INFEKSI LUKA OPE…

Infeksi nosokomial merupakan penyebab utama tingginya angka kesakitan dan kematian di dunia. Pada tahun 2002 CDC memperkirakan angka kejadian infeksi nosokomial di rumah sakit 1,7 juta orang dan sekitar 99.000 orang meninggal karena infeksi ini.Infeksi luka operasi (ILO) merupakan salah satu dari infeksi nosokomial mayoritas yang terjadi di rumah sakit. Penggunaan antibiotik profilaksis yang se…