Striatin-Dependent Membrane Estrogen Receptor Signaling and Vasoprotection by Estrogens

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Striatin-Dependent Membrane Estrogen Receptor Signaling and Vasoprotection by Estrogens

Bobik A - Personal Name;

Estrogen activates multiple signaling pathways in most target cells and tissues, including those within the cardiovascular system. Functional ERs, ER and ER, are expressed on cardiomyocytes in the heart and by endothelial and smooth muscle cells within blood vessels. Early studies indicated that
ERs are ligand-activated transcription factors, which exist primarily in the nucleus complexed with chaperones.

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Language: English
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Classification: NONE
Content Type: LITERATURE
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Subject(s): Posafit
Striatin
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Statement of Responsibility: Circulation. 2012;126:1941-1943

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