Meta‑analysis on the use of hyaluronic acid gel to prevent intrauterine adhesion after intrauterine operations

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Meta‑analysis on the use of hyaluronic acid gel to prevent intrauterine adhesion after intrauterine operations

Zheng F - Personal Name;

Intrauterine adhesion (IUA) is a severe complication that occurs following abortion, and hyaluronic acid gel has been used to prevent IUA following intrauterine operation. The present study aimed to systematically evaluate the efficacy of hyaluronic acid gel in preventing IUA following intrauterine operation. In the current study, a literature search was performed using PubMed, Cochrane Library and EMbase databases for randomized controlled clinical trials that used hyaluronic acid gel as an adjuvant therapy following intrauterine operation. The terms ‘hyaluronic acid’, ‘intrauterine adhesions’, ‘Asherman's
syndrome’, ‘IUA’, ‘dilatation and curettage’, ‘abortion’ and ‘hysteroscopic’ were used to search for articles published online before July 31, 2018. RevMan 5.3 software was used to analyze the indicators of uterine cavity adhesion formation and pregnancy rates following intrauterine operation.

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Language: English
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Content Type: LITERATURE
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Subject(s): Hycel
Hyaluronic Acid
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Statement of Responsibility: EXPERIMENTAL AND THERAPEUTIC MEDICINE 19: 2672-2678, 2020

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