PRODUCT LITERATURE

Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Recommendations, and New Trends

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The significant physical and emotional effects of chemotherapy-induced nausea and vomiting (CINV) are experienced by cancer patients. Severe symptoms decrease the patient’s quality of life and potentially deters further treatment. The five main forms of CINV (i.e., acute, delayed, anticipatory, breakthrough, and refractory) require different treatment regimens, which often include 5-HT3 receptor antagonists, NK1 receptor antagonists, and corticosteroids. Despite a significant amount of research and development of antiemetic agents, management of CINV remains a great challenge with many needs waiting to be adequately addressed, such as controlling nonacute CINV, developing appropriate CINV treatment protocols for multiple-day chemotherapy patients, and
providing options for those prone to CINV despite treatment. Further research is required to optimize CINV management for these patients

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: .,

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Language

English

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NONE

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LITERATURE

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Subject(s)

Chemotherapy-induced nausea and vomiting

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Statement of Responsibility

Cancer Treatment and Research Communications 26 (2021) 100278

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