PRODUCT LITERATURE
Multicenter nonrandomized trial of ramosetron versus palonosetron in controlling chemotherapy-induced nausea and vomiting for colorectal cancer
Chemotherapy-induced nausea and vomiting (CINV) have a negative impact on patients’ quality of life and
frequently pointed to as a major factor for treatment abandonment. Serotonin (5-HT3) receptor antagonist is considered
as key treatment for CINV. Ramosetron and palonosetron are recently developed 5-HT3 receptor antagonists and known
as more superior than other first-generation 5-HT3 receptor antagonists. The purpose of this study was to compare the
efficacy of ramosetron and palonosetron and determine which drug is more effective for prevention of CINV.
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