PRODUCT LITERATURE

Palonosetron in pediatric patients: A single-center, retrospective evaluation of policy and clinical practice guideline discordance

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Clinical practice guidelines (CPGs) recommending palonosetron for the prevention and management of
chemotherapy-induced nausea and vomiting (CINV) were adapted for use at our institution. Palonosetron was restricted
for use in patients experiencing breakthrough CINV and receiving highly emetogenic chemotherapy (HEC) or undergoing
stem cell transplant conditioning and in patients with refractory CINV receiving HEC. Given the significant cost of palo-
nosetron, we aimed to determine the proportion of chemotherapy blocks where palonosetron use was discordant with
the institutional policy or source CPG.

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Detail Information

Series Title

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Call Number

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Publisher

: .,

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

LITERATURE

Media Type

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Carrier Type

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Edition

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Subject(s)

Pediatric
Palofer
Palonosetron

Specific Detail Info

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Statement of Responsibility

J Oncol Pharm Practice 2025, Vol. 31(2) 251–255

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