THERAPEUTIC CLASS

The safety of high-dose rocuronium bromide in general anesthesia for spinal surgery and its effects on muscle relaxation

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This study aimed to investigate the effects of high-dose rocuronium bromide in general anesthesia for spinal surgery and analyze its safety. Methods: A total of 90 patients with spine diseases who underwent elective spinal surgery in our hospital were enrolled as study subjects, and were divided into 2-fold group (intraoperative administration of 0.6 mg/kg rocuronium bromide, n=30), 3-fold group (0.9 mg/kg rocuronium bromide, n=30) and 4-fold group (1.2 mg/kg rocuronium bromide, n=30). The effects of rocuronium bromide on muscle relaxation, the operative time and the incidence of adverse reactions were compared among the three groups. Results: The onset time of muscle relaxation in the 4-fold group was significantly lower than that in 2-fold and 3-fold groups. The
duration of muscle relaxation and duration of action in the 4-fold group were significantly higher than those in the 2-fold and 3-fold groups (P

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Publisher

: .,

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

LITERATURE

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Carrier Type

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Edition

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Subject(s)

ROCUM
Rocuronium Bromide
Muscle Relaxation

Specific Detail Info

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Statement of Responsibility

Am J Transl Res 2021;13(7):8110-8117

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