PRODUCT LITERATURE

The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients

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Aim: We aimed to assess the efficacy of MLC601 on functional recovery in patients givenMLC601 after an ischemic stroke.
Methods: This is a retrospective cohort study comparing poststroke patients given open-label MLC601 (n = 30; 9 female) for three months
and matching patients who did not receive MLC601 from our Stroke Data Bank. Outcome assessed was modified Rankin Scale (mRS) at three months and analyzed according to: (1) achieving a score of 0-2, (2) achieving a score of 0-1, and (3) mean change
in scores from baseline. Results. At three months, 21 patients on MLC601 became independent as compared to 17 patients not
on MLC601 (OR 1.79; 95% CI 0.62–5.2; P = 0.29). There were twice as many patients (n = 16) on MLC601 who attained mRS
scores similar to their pre stroke state than in the non-MLC601 group (n = 8) (OR 3.14; 95% CI 1.1–9.27; P = 0.038). Mean improvement in mRS from baseline was better in the MLC601 group than in the non-MLC601 group (−1.7 versus −0.9; mean difference −0.73; 95% CI −1.09 to −0.38;P < 0.001). Conclusion: MLC601 improves functional recovery at 3months postischemic stroke. An ongoing large randomized control trial of MLC601 will help validate these results

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: .,

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

LITERATURE

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Edition

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Subject(s)

NeuroAid
MLC601
Postischemic Stroke Patients

Specific Detail Info

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Statement of Responsibility

Rehabilitation Research and Practice Volume 2012, Article ID 506387, 5 pages

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