PRODUCT LITERATURE

Omeprazole: Effective, Convenient Therapy for Zollinger-Ellison Syndrome

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The acute and long-term effects of omeprazole on gastric acid secretion were examined in 11 patients with Zollinger-Ellison syndrome. Basal gastric acid secretion was inhibited by 50% 3 h after a single 60-mg dose of omeprazole and 78% 4 h after administration
of omeprazole. Patients were treated with a single daily dose of omeprazole, and the dose requirement was defined as the lowest dose of omeprazole that would reduce gastric acid secretion to < 10 mEq/h during the last hour before the next dose. The mean daily dose requirement was 70 mg (range 20-160 mg).

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Detail Information

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Publisher

: .,

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

TEXTBOOK

Media Type

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Carrier Type

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Edition

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Subject(s)

Gastrofer
Omeprazole
Zollinger-Ellison Syndrome

Specific Detail Info

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Statement of Responsibility

GASTROENTEROLOGY 1985;88:939-44

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