PRODUCT LITERATURE
EFFICACY OF POLYGELINE PRELOADING IN PREVENTION OF HYPOTENSION FOLLOWING CSEA
One hundred ASA grade I and II patients in the age group of 18 to 60 years of either sex undergoing lower abdominal or lower limb surgeries under combined spinal epidural anaesthesia (CSEA) using 0.5% bupivacaine were studied for efficacy of polygeline preloading as compared to equal volume of ringer's lactate for prevention of hypotension. They were randomly divided in two groups of 50 each. Group I patients received 500 ml of polygeline and group II, 500 ml ringer's lactate. The study revealed that 9 (18%) patients in group I showed hypotension as against 25 (50%) in group II. The difference was statistically highly significant p < 0.001. While only 2(4%) patients in group I showed severe grade of hypotension (>30% fall of baseline value MAP) against 5 (10%) patients in group II, requiring mephentermine in addition to volume loading
No other version available