PRODUCT LITERATURE

Effectivity and safety of mahkota dewa fruit extract compared to meloxicam (phaleria macrocarpa fructus) on osteoarthritis

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Osteoarthritis (OA) is the most common musculoskeletal disease. World Health Organization (WHO) estimates that 10% of the aged over 60 year population have this disease. The aim of OA treatment is to reduce pain, which is the most OA patients chief
complaint. People in Indonesia are very interested in use of herbal therapies from original traditional plant to treat
pain now, one of the traditional plants that are known have a benefit is Phaleria macrocarpa or Mahkota Dewa fruit.
Phaleria macrocarpa has been shown to decrease the degree of inflammation of OA animal model experiments.
In order to know what is the effect of this fruit extract to reduce degrees of pain and change the levels of IL-1, IL-6, TNF-α in the blood as the marker of inflammation of patients with knee OA, and what is the effects to liver, kidney and haematology in the Indonesian population has not been investigated

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Language

English

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Classification

NONE

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Subject(s)

Phaleria macrocarpa
Mahkota Dewa

Specific Detail Info

Indonesian Journal of Rheumatology 2016; Vol 8:20-25

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