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EFFECT OF CENTELLA ASIATICA ON MILD COGNITIVE IMPAIRMENT (MCI) AND OTHER COMMON AGE-RELATED CLINICAL PROBLEMS


Centella asiatica is an herb used since ancient time in Ayurveda to improve mild cognitive functioning. The current study aimed to managing the cognitive functioning in elderly with mild cognitive impairment (MCI) and other age related problems. MCI is a serious
problem which may be converted into Alzheimer disease. Although the concept of MCI is based on the presence of specific cognitive deficits, several study shows that these subjects can be develop depression, disruptive behavior (e.g agitation, aggression). The present
study has conducted in sixty elderly subjects with written consent, registered at the geriatric out patient clinic at S.S. Hospital, BHU with age group 65 and above. The Diagnostic tools used in this study were Mini Mental State Examination, Activities of Daily Living, Instrumental Activities of Daily living and Yesavage Geriatric Depression scale. The Centella asiatica extract was prescribed in dosage of 500mg twice a day (1000 mg daily) for 6 months. An favorable improvement is observed in depression and other age related conditions like Hypertension, insomnia, loss of appetite, constipation etc.


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English
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NONE
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Digest Journal of Nanomaterials and Biostructures Vol. 3, No.4, December 2008, p. 215 - 220
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