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LITERATURE

Oral Methylprednisolone Acetate (Medrol Tablets) for Seasonal Rhinitis: Examination of Dose and Symptom Response


The authors compared the effect of several doses an oral corticosteroid on symptom profile and severity in ragweed hay fever. Thirty-one patients were randomized to receive 06, 12, or 24 mg methylprednisolone (Medrol Tablets [MP], Upjohn, Kalamazoo, MI). A baseline week in which no treatment was given preceded the treatment comparison. At the end of this week, symptom diaries showed that most of the subjects were experiencing
moderate or severe symptoms. The corticoid produced dose-related reduction in all symptoms


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English
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The Journal of Clinical Pharmacology, 33(9), 816–822
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