Image of Ketamine spares morphine consumption after transthoracic lung and heart surgery without adverse hemodynamic effects

LITERATURE

Ketamine spares morphine consumption after transthoracic lung and heart surgery without adverse hemodynamic effects


Thoracotomy is associated with severe pain. Large doses of morphine can depress respiratory drive and compromise hemodynamic stability. Ketamine reduces hyperalgesia, prevents opioid tolerance and resistance and lowers morphine consumption. At sub-anesthetic (≤500g/kg) doses, ketamine rarely produces undesirable hemodynamic alterations. We hypothesized that by combining a sub-anesthetic dose of ketamine with morphine, we could effectively control pain with less morphine and minimize
drowsiness, while maintaining safe hemodynamic and respiratory parameters


Availability

Kemidex-002Available

Detail Information

Series Title
-
Call Number
-
Publisher : .,
Collation
-
Language
English
ISBN/ISSN
-
Classification
NONE
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Specific Detail Info
Pharmacological Research 58 (2008) 38–44
Statement of Responsibility

Other version/related

No other version available


File Attachment



Information


RECORD DETAIL


Back To Previous