PRODUCT LITERATURE

Intravenous sub-anesthetic ketamine for perioperative analgesia

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Ketamine, an N-methyl-d-aspartate antagonist, blunts central pain sensitization at sub-anesthetic doses (0.3 mg/kg or less)
and has been studied extensively as an adjunct for perioperative analgesia. At sub-anesthetic doses, ketamine has a minimal
physiologic impact though it is associated with a low incidence of mild psychomimetic symptoms as well as nystagmus and
double vision. Contraindications to its use do exist and due to ketamine’s metabolism, caution should be exercised in patients
with renal or hepatic dysfunction. Sub-anesthetic ketamine improves pain scores and reduces perioperative opioid consumption
in a broad range of surgical procedures. In addition, there is evidence that ketamine may be useful in patients with opioid
tolerance and for preventing chronic postsurgical pain.

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Detail Information

Series Title

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Call Number

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Publisher

: .,

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Kemidex
Ketamine HCL

Specific Detail Info

Journal of Anaesthesiology Clinical Pharmacology 2016

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