Image of Evaluation of the Efficacy and Tolerability of Combination Therapy With Candesartan Cilexetil and Amlodipine Besilate Compared With Candesartan Cilexetil Monotherapy and Amlodipine Besilate Monotherapy in Japanese Patients With Mild-to-Moderate Essential Hypertension :A Multicenter,12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

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Evaluation of the Efficacy and Tolerability of Combination Therapy With Candesartan Cilexetil and Amlodipine Besilate Compared With Candesartan Cilexetil Monotherapy and Amlodipine Besilate Monotherapy in Japanese Patients With Mild-to-Moderate Essential Hypertension :A Multicenter,12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study


Blood pressure is reported to be insufficiently controlledin>50% of patients with hypertension. Guidelines for the management of hypertension recommend using drugs with different mechanisms of action when >1 agent is needed to achieve the blood pressure target. The combination of an angiotens inreceptor blocker and a calcium channel blockeris recommended asthe preferred antihypertensive medication combination, and candesartan cilexetil (CC) and amlodipine besilate (AML) are commonly used in Japan.


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English
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NONE
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Clinical Therapeutics Volume 34,Number 4, 2012
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