PRODUCT LITERATURE

Intrapulmonary concentrations of meropenem administered by continuous infusion in critically ill patients with nosocomial pneumonia: a randomized pharmacokinetic trial

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Optimal antimicrobial drug exposure in the lung is required for successful treatment outcomes for
nosocomial pneumonia. Little is known about the intrapulmonary pharmacokinetics (PK) of meropenem when
administered by continuous infusion (CI). The aim of this study was to evaluate the PK of two dosages of
meropenem (3 g vs 6 g/day by CI) in the plasma and epithelial lining fluid (ELF) in critically ill patients with
nosocomial pneumonia.

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Detail Information

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Publisher

: .,

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Language

English

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Classification

NONE

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Edition

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Subject(s)

Meropenem
Population pharmacokinetcs
Critically ill patients

Specific Detail Info

Critical Care (2020) 24:55

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