PRODUCT LITERATURE
Role of Vitamin D in the Metabolic Syndrome
The prevalence of hypovitaminosis D has risen in developed countries over the past
few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D
deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is
clinically defined by a set of metabolic and vascular disorders. The objective of this study was to
review scientific evidence on the relationship between MetS and vitamin D deficiency to support
the development of prevention strategies and health education programs. An inverse relationship
has been reported between plasma vitamin D concentrations and the features that define MetS, i.e.,
elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides,
glycosylated hemoglobin, and a high body mass index. Numerous studies have described the
benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions
to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS
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