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Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial

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Heart failure (HF) is a common and highly morbid cardiovascular disorder. Oxidative stress worsens HF, and uric acid (UA) is a useful oxidative stress marker. The novel antihyperuricemic drug febuxostat is a potent non-purine selective xanthine oxidase inhibitor. The
present study examined the UA-lowering and prognostic effects of febuxostat in patients with HF compared with conventional allopurinol.

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Series Title

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: .,

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Language

English

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Classification

NONE

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Edition

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Subject(s)

Febuxostat
Allopurinol
Uric Acid

Specific Detail Info

Journal of International Medical Research 49(12) 1–15

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