Image of Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial

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Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial


Heart failure (HF) is a common and highly morbid cardiovascular disorder. Oxidative stress worsens HF, and uric acid (UA) is a useful oxidative stress marker. The novel antihyperuricemic drug febuxostat is a potent non-purine selective xanthine oxidase inhibitor. The
present study examined the UA-lowering and prognostic effects of febuxostat in patients with HF compared with conventional allopurinol.


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English
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Journal of International Medical Research 49(12) 1–15
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