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Comparison of uric acid reduction and renal outcomes of febuxostat vs allopurinol in patients with chronic kidney disease


Whether the clinical trial treatment effect of urate-lowering therapy (ULT) in patient with chronic kidney disease (CKD) is generalizable to real-word settings is unclear. This study aimed to compare febuxostat with allopurinol for uric acid reduction and renal protection in patients with CKD. Adult CKD patients newly treated with ULT were identified using electronic health records from 2010 to 2015 from a large healthcare delivery system in Taiwan. Patients with renal replacement therapy or undergoing ULT for


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English
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NONE
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https://doi.org/10.1038/s41598-020-67026-1
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