PRODUCT LITERATURE

Management of Tetanus: A Review

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Large-scale immunization programs have resulted in a dramatic decline in the incidence of tetanus in the US. Other factors such as improvements in wound care
management, use of sedating and paralytic agents, and advances in supportiv and intensive care measures (eg, airway and ventilatory support) have also contributed to
the decline in the morbidity and mortality from tetanus. The diagnosis of tetanus is made clinically and by exclusion of other conditions in the differential diagnosis. Laboratory tests are not helpful in confirming the diagnosis of tetanus. All patients suspected of tetanus should initially be managed in the intensive care
unit (ICU). The cornerstone of therapy revolves around six principles: 1) stabilization of the airway and ventilation, 2) aggressive control and management of tetanic
muscle spasms and rigidity, 3) neutralization of tetanus toxin (tetanospasmin) with passive immunization, 4) antibiotics in an attempt to eradicate the source of toxin
production, 5) control of autonomic instability, and 6) general wound and supportive care.

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: .,

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Language

English

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Classification

NONE

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Edition

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Subject(s)

Tetagam
Tetanus

Specific Detail Info

Current Treatment Options in Infectious Diseases 2001, 3:209–216

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