THERAPEUTIC CLASS
Current Concepts of Premature Ventricular Contractions
Premature ventricular contractions (PVCs) are early depolarizations of the myocardium originating in the ventricle.
PVCs are common with an estimated prevalence of 40% to 75% in the general population on 24- to 48-hour Holter
monitoring. Traditionally, they have been thought to be relatively benign in the absence of structural heart disease
but they represent increased risk of sudden death in structural heart disease. Especially in ischemic heart disease, the
frequency and complexity of PVCs is associated with mortality
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