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Histamine release and therapy of severe dermatographism


A case of unusually severe dermatographism is reported in which baseline plasma histamine levels were repeatedly elevated and histamine release into the circulation was demonstrable upon challenge by scratching the skin. Passive transfer was positive when the patient was challenged after a 48-hr interval, and the responsible factor was heat labile consistent with an IgE-dependent mechanism


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English
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NONE
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Specific Detail Info
J ALLERGY CL/N IMMUNOL 68:/03, 1981
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