THERAPEUTIC CLASS
Correlation between urinary albumin to creatinine ratio and systemic glycocalyx degradation in pediatric sepsis
Increased capillary permeability in sepsis is associated with several complications and worse outcomes. Glycocalyx
degradation, marked by increased serum syndecan-1 levels, alters vascular permeability, which can manifest as albuminuria in
the glomerulus. Therefore, elevated urinary albumin to creatinine ratio (ACR) potentially provides an index of systemic glycocalyx
degradation. The aim of this study was to analyze the correlation between urinary ACR and serum syndecan-1 levels
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