THERAPEUTIC CLASS
The Role of Hormones in Male Sexual Function
Male sexual dysfunction has many different causes and is often multifactorial in nature. We aim to review the effects that testosterone (T), estrogen, thyroid hormone, prolactin (PRL), and cortisol have on male sexual function. Recent Findings T deficiency can cause decreased libido and diminished erectile function. Estrogen is necessary for sexual drive but is postulated to inhibit erectile function when elevated. Hyperthyroidism is associated with premature ejaculation (PE), hypothyroidism is associated with delayed ejaculation (DE), and both are associated with erectile dysfunction (ED). Hyperprolactinemia is associated with ED and can cause fertility issues. The role of corticosteroids is largely unknown. Summary While hormonal disorders can largely influence male sexual health, resolution of sexual dysfunction is achieved in most cases by normalization of hormone levels
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