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LITERATURE

Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: a pharmacokineticpharmacodynamic analysis


Oral midazolam is widely used for preoperative sedation in children. We have studied the pharmacokinetics (PK) of both midazolam and its active l-hydroxy metabolite and their contributions to sedative effect in 45 children attending for day surgery.


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English
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NONE
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Specific Detail Info
British Journal of Anaesthesia 89 (3): 428-37 (2002)
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