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The use of functional epirubicin liposomes to induce programmed death in refractory breast cancer

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Currently, chemotherapy is less efficient in controlling the continued development of breast cancer because it cannot eliminate extrinsic and intrinsic refractory cancers. In this study, mitochondria were modified by functional epirubicin liposomes to eliminate refractory cancers through initiation of an apoptosis cascade. The efficacy and mechanism of epirubicin liposomes were investigated on human breast cancer cells in vitro and in vivo using flow cytometry, confocal microscopy, high-content screening system, in vivo imaging system, and tumor inhibition in mice

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: .,

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Language

English

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NONE

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Subject(s)

Epirubisin

Specific Detail Info

International Journal of Nanomedicine 2017:12 4163–4176

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