PRODUCT LITERATURE
Phase I Trial of Docetaxel Administered by Weekly Infusion in Patients With Advanced Refractory Cancer
Docetaxel is a highly active antineoplastic agent; however, grade IV leukopenia occurs in the large majority of patients treated with a dose of 100 mg/m2
every 3 weeks. Recent experience with weekly paclitaxel has demonstrated a bone marrow-sparing effect when a weekly administration schedule is used. We
investigated a weekly schedule of docetaxel in an attempt to alter the toxicity profile and improve the therapeutic index
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