PRODUCT LITERATURE

Intravenous nitroglycerin in acute myocardial infarction

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Vasodilator therapy has been shown to improve ventricular function in patients with left ventricular failure complicating acute myocardial infarction. Sublingual nitroglycerin also improves ventricular function in these patients but its effects are transient and variable. Infusion of intravenous nitroglycerin in 12
patients with acute infarction resulted in a decrease in left ventricular filling pressure from a mean of 22 2 mm Hg to 12 ± 1 mm Hg (P < 0.001) associated with a 7 mm Hg decrease in mean arterial pressure (P < 0.05). Since stroke work index did not change significantly, this represents an improvement in ventricular performance and/or an alteration in ventricular compliance.

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: .,

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Language

English

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NONE

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Subject(s)

NTG

Specific Detail Info

Circulation. 1975;51:132-139

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