PRODUCT LITERATURE

Clinical and Circulatory Effects of Isosorbide Dinitrate ; Comparison with Nitroglycerin

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In order to resolve current controversies on isosorbide dinitrate (ISDN), we employed a particularly sensitive testing protocol to evaluate effects of sublingual ISDN and nitroglycerin on the exercise capacity of patients with angina. Ten minutes after ISDN 21 of 23 patients exercised longer (average 2.7 minutes, P < 0.001) than after placebo. Benefit was evident in only a minority of patients tested one hour and in none tested two hours after either ISDN or nitroglycerin

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Language

English

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NONE

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Subject(s)

NTG

Specific Detail Info

Circulation . 1971 May;43(5):629-40

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