Image of Inhaled budesonide in the management of acute worsenings and exacerbations of asthma: A review of the evidence

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Inhaled budesonide in the management of acute worsenings and exacerbations of asthma: A review of the evidence


The use of systemic corticosteroids, together with bronchodilators and oxygen therapy, has become established for the management of acute asthma. These agents are undoubtedly effective, but are also associated with problems such as metabolic adverse effects. Inhaled corticosteroids (ICS) offer potential benefit in the acute setting because they are delivered directly to the airways. They are also likely to reduce systemic exposure, which would lead in turn to reductions in rates of unwanted systemic effects. In order to evaluate the role of budesonide in the management of acute asthma exacerbations we conducted a review of the literature and critically evaluated the rationale for the use of ICS in general in this setting


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English
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NONE
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Respiratory Medicine (2007) 101, 685–695
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