PRODUCT LITERATURE

Gonadotropin-releasing hormone and its receptor in normal and malignant cells

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Gonadotropin-releasing hormone (GnRH) is the hypothalamic factor that mediates reproductive competence. Intermittent GnRH secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of the gonadotropins, LH and FSH. LH and FSH then
stimulate sex steroid hormone synthesis and gametgenesis in the gonads to ensure reproductive
competence. The pituitary requires pulsatile stimulation by GnRH to synthesize and release the
gonadotropins LH and FSH

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: .,

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Language

English

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NONE

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Subject(s)

Pamorelin

Specific Detail Info

Endocrine-Related Cancer (2004) 11 725–748

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