Citicoline: neuroprotective mechanisms in cerebral ischemia

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Citicoline: neuroprotective mechanisms in cerebral ischemia

Adibhatla RM - Personal Name;

Cytidine-5 ¢-diphosphocholine (citicoline or CDP-choline), an intermediate in the biosynthesis of phosphatidylcholine (PtdCho), has shown bene®cial effects in a number of CNS injury models and pathological conditions of the brain. Citicoline improved the outcome in several phase-III clinical trials of stroke, but provided inconclusive results in recent clinical trials.

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Neulin PS - 001

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Language: English
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Subject(s): Neulin PS
Specific Detail Info: Journal of Neurochemistry 2002;80:12-23
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