PRODUCT LITERATURE

Drug-Drug Interaction Profiles of Proton Pump Inhibitors

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Proton pump inhibitors (PPIs) are widely prescribed for the treatment of gastric acid-related disorders and the eradication of Helicobacter pylori. In addition, they are routinely prescribed for the prevention of gastrointestinal bleeding in patients receiving a dual antiplatelet therapy consisting of clopidogrel and aspirin (acetylsalicylic acid) after myocardial infarction or percutaneous coronary intervention and stenting. Because PPIs are given to these patients for long periods, there is a concern about the potential
for clinically significant drug-drug interactions (DDIs) with concomitantly administered medications.

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Vomizole

Specific Detail Info

Clin Pharmacokinet 2010; 49 (8): 509-533

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