Image of Pharmacokinetics of Pantoprazole in Patients with Moderate and Severe Hepatic Dysfunction

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Pharmacokinetics of Pantoprazole in Patients with Moderate and Severe Hepatic Dysfunction


Patients with impaired hepatic function usually require gastric acid suppressant therapy but are at increased risk for drug interactions and may require dosage adjustments. The proton pump inhibitor pantoprazole is rapidly absorbed and eliminated, primarily by cytochrome P450 (CYP) 2C19 isozymes.


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English
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NONE
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CLINICAL THERAPEUTICS®/VOL. 23, NO. 8, 2001
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