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A COMPARISON OF SUCRALFATE AND RANITIDINE FOR THE PREVENTION OF UPPER GASTROINTESTINAL BLEEDING IN PATIENTS REQUIRING MECHANICAL VENTILATION


Critically ill patients who require mechanical ventilation are at increased risk for gastrointestinal bleeding from stress ulcers. There are conflicting data on the effect of histamine H2-receptor antagonists and the cytoprotective agent sucralfate on rates of gastrointestinal bleeding, ventilator-associated pneumonia, and mortality


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English
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NONE
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N Engl J Med 1998;338:791-7
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