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LITERATURE

Roflumilast: In Chronic Obstructive Pulmonary Disease


Roflumilast is an orally administered, selective phosphodiesterase 4 inhibitor that is a novel treatment for patients with severe chronic obstructive pulmonary disease (COPD). Across four randomized, double-blind, multinational trials in patients with moderate to severe or severe COPD, roflumilast 500 microg/day produced significantly greater improvements from baseline than placebo in pre- and post-bronchodilator forced expiratory volume in 1 second (FEV(1))


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English
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NONE
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Drugs. 2010 Aug 20;70(12):1615-27.
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