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Eff ect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial

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Roflumilast reduces exacerbations in patients with severe chronic obstructive pulmonary disease. Its eff ect in patients using fi xed combinations of inhaled corticosteroids and longacting β2 agonists is unknown. We postulated that rofl umilast would reduce exacerbations in patients with severe chronic obstructive pulmonary disease at risk for exacerbations, even in combination with inhaled corticosteroid and longacting β2 agonist treatment

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English

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NONE

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Forespi

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