PRODUCT LITERATURE

Dissolution Testing of Orally Disintegrating Tablets

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Orally disintegrating tablets (ODT) are solid dosage forms that disintegrate in the oral cavity leaving an easy-to-swallow residue.The disintegration times are generally less than one minute.For orally disintegrating tablets,taste-masking of bitter or objectional-tasting drug substances is critical.The taste-masking aspect plays a significant role in dissolution method development,specifications,and testing.The USP 2
paddle apparatus is the most suitable and common choice for orally disintegrating tablets.Discriminating, robust dissolution methods are extremely useful for monitoring process optimization and changes during scale-up of taste-masked bulk drug and tablet manufacture.

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: .,

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English

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NONE

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Subject(s)

Vometa FT

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