PRODUCT LITERATURE

Fenofibrate: A Review of its Use in Dyslipidaemia

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Fenofibrate is a fibric acid derivative indicated for the treatment of severe hypertriglyceridaemia and mixed dyslipidaemia in patients who have not responded to nonpharmacological therapies. The lipid-modifying effects of fenofibrate are mediated by the activation of peroxisome proliferator-activated receptor-a. Fenofibrate also has nonlipid, pleiotropic effects (e.g. reducing levels of fibrinogen, C-reactive protein and various pro-inflammatory markers, and improving flow-mediated dilatation) that may contribute to its clinical efficacy, particularly in terms of improving microvascular outcomes.

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: .,

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Language

English

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NONE

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Subject(s)

Trolip

Specific Detail Info

Drugs 2011; 71 (14): 1917-1946

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