PRODUCT LITERATURE
A review of the safety and efficacy of nebivolol in the mildly hypertensive patient
Nebivolol is a third generation beta-blocker, which can be distinguished from other beta-blockers by its hemodynamic profi le. It combines beta-adrenergic blocking activity with a vasodilating effect mediated by the endothelial L-arginine nitric oxide (NO) pathway. The
effects of nebivolol have been compared with other beta-blockers and also with other classes of antihypertensive agents. In general, response rates to treatment are higher, and the frequency and severity of adverse events are either comparable or lower with nebivolol
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