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Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

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Vitamin E (&agr;-tocopherol) is thought to have a role in prevention of atherosclerosis, through inhibition of oxidation of low-density lipoprotein. Some epidemiological studies have shown an association between high dietary intake or high serum concentrations of &agr;-tocopherol and lower rates of ischaemic heart disease. We tested the hypothesis that treatment with a high dose of &agr;-tocopherol would reduce subsequent risk of myocardial infarction (MI) and cardiovascular death in patients with established ischaemic heart disease.

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Seloxy

Specific Detail Info

Lancet 1996; 347: 781-86

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