PRODUCT LITERATURE

Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults

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On days 1 and 5, intragastric pH was >4.0 significantly longer with esomeprazole than lansoprazole (least-squares means: day 1, 40.0% vs.
33.6%; day 5, 61.9% vs. 45.4%; both P < 0.0001). During the first 4 h of pH monitoring, intragastric pH was >4.0 significantly longer on days
1 and 5 with esomeprazole than lansoprazole (P < 0.0001). Kaplan–Meier estimates of median hours to stable pH >4.0 were 4.92 for esomeprazole and 5.75 for lansoprazole (P = 0.0014 for test on Gehan scores).

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: .,

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Language

English

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NONE

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Subject(s)

Esoferr

Specific Detail Info

Aliment Pharmacol Ther 27, 483–490

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