PRODUCT LITERATURE

The Use and Effectiveness of Rituximab Maintenance in Patients with Follicular Lymphoma Diagnosed Between 2004 and 2007 in the United States

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A total of 1439 patients completed R-based induction therapy, 1186 of whom met all inclusion criteria (541 patients received R-maintenance and 645 patients were observed). Characteristics that were found to be predictive of receiving R-maintenance were histology grade (1/2), Ann Arbor stage of disease (III/IV), geographic region (region other than the West), and practice setting (community practice). With a median followup of 5.7 years, R-maintenance was associated with superior PFS (hazards ratio [HR], 0.68; 95% confidence interval [95% CI], 0.56- 0.84 [P5.0003]) and TTNT (HR, 0.66; 95% CI, 0.52-0.84 [P5.0007]). No significant difference in OS was observed (HR, 0.81; 95% CI, 0.58-1.14 [P5.23]).

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Redditux

Specific Detail Info

Cancer 2014;120:1830–7

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