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LITERATURE

More Epidural than Intravenous Sufentanil is Required to Provide Comparable Postoperative Pain Relief


The extent to which epidurally administered sufentanil acts directly on spinal opioid receptors remains controversial. We tested the hypothesis that smalldose boluses of sufentanil, given epidurally or IV, provide comparable analgesia at similar plasma
sufentanil concentrations. The lipophilicity of sufentanil makes it likely to be absorbed into fat surrounding the epidural space


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English
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NONE
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Specific Detail Info
Anesth Analg 2001;93:472–6
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