THERAPEUTIC CLASS

Role of fever and ambient temperature in COVID-19

---

The role of fever in COVID-19 has not been studied in large
studies. In our review of the literature, only two studies have
related the ambient temperature or fever to the outcomes of
the COVID-19 patients. In a non-peer-reviewed observational
study, the high ambient temperature was correlated with
decreased mortality in COVID-19 patients in Wuhan and
Hubei provinces; however, no data on the patient’s tempera-
ture was available in the study which limits the derivation of
any conclusion from the study [20]. Regular high fever in
COVID-19 is considered to be an indicator of severe infection.
In a study of 201 patients in Wuhan, high fever (>39°C) was
associated with a higher likelihood of acute respiratory distress
syndrome (HR, 1.77; 95% CI, 1.11–2.84), and lower risk of
mortality (HR, 0.41; 95% CI, 0.21–0.82) [21]. The preliminary
results may point toward an association of improved prog-
nosis in terms of mortality in severe COVID-19 patients with
fever. The study was not geared toward identifying the impact
of fever or antipyretics in COVID-19 patients, however, it pro-
vides a glimpse into the possible impact of fever on COVID-19
prognosis.

---

Availability

Detail Information

Series Title

-

Call Number

-

Publisher

: .,

Collation

-

Language

English

ISBN/ISSN

-

Classification

NONE

Content Type

Therapeutic Class

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Covid-19

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment